Guidelines for global use

The Brighton Collaboration is committed to develop guidelines for collection, analysis and presentation of vaccine safety data intended to enhance data comparability within and across clinical trials, surveillance systems, and post-licensure clinical studies.

Working Groups

Working Groups work as multidisciplinary teams consisting of 5 - 20 volunteers with relevant experience in patient care, public health, clinical trials, safety surveillance and safety assessment from developed and developing countries. Volunteers are actively sought by the Brighton Team, can be recommended, or can volunteer themselves.

Method

Case definition development follows an established standard "Brighton method". This is based on systematic review of current evidence, consensus formation, structured peer review and scientific publication.

Brighton Guidelines

Several of our guidelines are endorsed by the World Health Organization (WHO) and the UN Council for International Organizations of Medical Sciences (CIOMS). Others were developed for the European Centre of Disease Prevention and Control (ECDC) and are in review for endorsement.