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Posted on August 27, 2024

Comirnaty COVID-19 mRNA vaccine: standardized template with key considerations for a benefit-risk assessment

This manuscript uses the BRAVATO template to report the key considerations for a benefit-risk assessment of the coronavirus diseas...
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Posted on October 26, 2023August 22, 2024

Novavax COVID-19 Vaccine (NVX-CoV2373), a recombinant spike protein vaccine with Matrix-M adjuvant to prevent disease caused by SARS-CoV-2 viruses

This paper uses a BRAVATO protein template to review the features of Novavax’s recombinant adjuvanted spike protein vaccine to p...
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Posted on October 13, 2023October 13, 2023

Live-attenuated viral vaccines: standardized template for collection of key information for benefit-risk assessment

Several live-attenuated viral vaccine candidates are among the COVID-19 vaccines in development. The Brighton Collaboration Viral...
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Posted on October 13, 2023October 13, 2023

Viral vector vaccines: standardized template for collection of key information for benefit-risk assessment

Many of the vaccines under development for COVID-19 involve the use of viral vectors. The Brighton Collaboration Benefit-Risk Asse...
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Posted on October 13, 2023October 13, 2023

Vaccines based on replication incompetent Ad26 viral vectors: Standardized template with key considerations for a risk/benefit assessment

Replication-incompetent adenoviral vectors have been under investigation as a platform to carry a variety of transgenes, and exp...
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Posted on October 4, 2023October 13, 2023

Modified Vaccinia Ankara (MVA) vaccine platform: standardized template for collection of key information for risk/benefit assessment

The Modified Vaccinia Ankara (MVA) vector system is being explored as a platform for development of multiple vaccines. This pape...
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Posted on April 6, 2023October 13, 2023

Medigen COVID-19 protein vaccine: standardized template with key considerations for a benefit/risk assessment

This paper uses a BRAVATO protein template to review the features of Medigen’s recombinant SARS-CoV-2 spike protein in prefusion...
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Posted on August 19, 2022October 13, 2023

Vaccines based on the replication-deficient simian adenoviral vector ChAdOx1: Standardized template with key considerations for a risk/benefit assessment

The Brighton Collaboration Benefit-Risk Assessment of VAccines by TechnolOgy (BRAVATO) was formed to evaluate the safety and other...
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Posted on August 19, 2022October 13, 2023

Inactivated viral vaccine against Chikungunya virus: standardized template with key considerations for a benefit/risk assessment

This paper uses the BRAVATO inactivated virus vaccine template to review the features of an inactivated whole chikungunya virus...
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Posted on August 19, 2022October 13, 2023

Moderna COVID-19 Vaccine (mRNA-1273): standardized template with key considerations for a benefit/risk assessment

This paper uses a BRAVATO nucleic acid template to review the features of Moderna’s rapid-response proprietary vaccine platform...
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Recent Posts

  • Safety by Numbers – February 2025February 19, 2025
  • Brighton Collaboration News — Sept 2024September 9, 2024
  • Lessons Learned from Vaccine Safety Surveillance EffortsSeptember 3, 2024
  • Comirnaty COVID-19 mRNA vaccine: standardized template with key considerations for a benefit-risk assessmentAugust 27, 2024
  • Safety by Numbers – August 2024August 14, 2024

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