Priority List of Adverse events of special interest for
MERS
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AESI: Pericarditis
Specific to MERS disease: 
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Click to access
AESI: Thrombosis / Thromboembolism
Specific to MERS disease:
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Click to access
AESI: Hemorrhagic disease
Specific to MERS disease:
Brighton Case Definition: End of 2023
Brighton CD Companion Guide: End of 2023
AESI: Thrombocytopenic Thrombosis Syndrome
Specific to vaccine: Adeno vectors
Brighton Case Definition: End of 2023
Brighton CD Companion Guide: End of 2023
AESI: Anaphylaxis
Specific to vaccine: All
vaccines
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Click to access
AESI: Thrombocytopenia
Specific to vaccine: All
vaccines
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Click to access
AESI: Vaccine-Associated Enhanced Disease
Specific to MERS disease:
Brighton Case Definition: Click to access
Brighton CD Companion Guide:Click to access
AESI: Acute aseptic arthritis
Specific to vaccine: VSV vector
Brighton Case Definition: Click to access
Brighton CD Companion Guide: End of 2023
AESI: Rhabdomyolysis
Specific to COVID-19 disease: –
Specific to vaccine: –
Brighton Case Definition: TBD
Brighton CD Companion Guide: TBD
AESI: Generalized convulsion
Specific to vaccine: All
vaccines
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Click to access
AESI: Aseptic meningitis
Specific to vaccine: Live attenuated viral vaccine
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Click to access
AESI: Acute Disseminated Encephalomyelitis
Specific to MERS disease:
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Click to access
AESI: Encephalitis
Specific to MERS disease:
Specific to vaccine: Live attenuated viral vaccine
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Click to access
AESI: Myelitis
Specific to MERS disease:
Specific to vaccine: Live attenuated viral vaccine
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Click to access
AESI: Guillain Barré Syndrome
Specific to vaccine: Some vaccines¹
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Click to access
AESI: Acute Respiratory Distress Syndrome
Specific to MERS disease:
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Click to access
AESI: Spontaneous abortion
Specific to MERS disease:
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Mid 2023
AESI: Stillbirth
Specific to MERS disease:
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Mid 2023
AESI: Maternal death
Specific to MERS disease:
Brighton Case Definition: Click to access
Brighton CD Companion Guide: TBD
AESI: Neonatal death
Specific to MERS disease:
Brighton Case Definition: Click to access
Brighton CD Companion Guide: TBD
1 Some seasonal influenza vaccines; monovalent H1N1 pandemic vaccine; COVID-19 ChAdOx-1 S vaccine.
Learn more about methods and results of the creation of the Priority List of potential Adverse events of special interest relevant to MERS vaccine trials HERE.
