Rift Valley Fever

Priority List of Adverse events of special interest for

Rift Valley Fever

 

AESI: Hemorrhagic disease
Specific to Rift Valley Fever disease: ✅
Brighton Case Definition: End of 2023
Brighton CD Companion Guide: End of 2023


AESI: Thrombocytopenic Thrombosis Syndrome
Specific to Rift Valley Fever disease: ✅
Specific to vaccine: Adeno vectors
Brighton Case Definition: End of 2023
Brighton CD Companion Guide: End of 2023

 

AESI: Anaphylaxis
Specific to vaccine: All
vaccines
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Click to access


AESI: Thrombocytopenia
Specific to vaccine: All
vaccines
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Click to access

AESI: Acute aseptic arthritis
Specific to vaccine: VSV vector
Brighton Case Definition: Click to access
Brighton CD Companion Guide: End of 2023

AESI: Generalized convulsion
Specific to Rift Valley Fever disease: ✅
Specific to vaccine: All
vaccines
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Click to access


AESI: Aseptic meningitis
Specific to vaccine: Live attenuated viral vaccine​
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Click to access


AESI: Loss of Vision (incl uveitis, retinitis, optic neuritis)
Specific to Rift Valley Fever disease: ✅
Brighton Case Definition: Prioritized, date TBD
Brighton CD Companion Guide: Prioritized, date TBD


AESI: Encephalitis
Specific to Rift Valley Fever disease: ✅
Specific to vaccine: Live attenuated viral vaccine
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Click to access


AESI: Myelitis
Specific to Rift Valley Fever disease: ✅
Specific to vaccine: Live attenuated viral vaccine
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Click to access


AESI: Guillain Barré Syndrome
Specific to Rift Valley Fever disease: ✅
Specific to vaccine: Some vaccines¹
Brighton CD Companion Guide: TBD

AESI: Acute Respiratory Distress Syndrome
Specific to Rift Valley Fever disease: ✅
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Click to access

AESI: Spontaneous abortion
Specific to Rift Valley Fever disease: ✅
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Mid 2023


AESI: Stillbirth
Specific to Rift Valley Fever disease: ✅
Brighton Case Definition: Click to access
Brighton CD Companion Guide: Mid 2023

1 Some seasonal influenza vaccines; monovalent H1N1 pandemic vaccine; COVID-19 ChAdOx-1 S vaccine.

Learn more about methods and results of the creation of the Priority List of potential Adverse events of special interest relevant to Rift Valley Fever vaccine trials HERE.

SEE ALL THE LISTS OF AESIs FOR THE CEPI PRIORITIZED PATHOGENS:

COVID-19
Chikungunya
Lassa Fever
Rift Valley Fever
COVID-19
Chikungunya
Lassa Fever
Rift Valley Fever